General Information:

Id: 3,314 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Rattus norvegicus
male
article
Reference: Senanayake GV et al.(2012) Mechanisms underlying decreased hepatic triacylglycerol and cholesterol by dietary bitter melon extract in the rat Lipids 47: 495-503 [PMID: 22457205]

Interaction Information:

Comment Rats fed diets containing the bitter melon (Momordica charantia L.) methanol fraction (MF), as compared to those without MF, showed: (1) no adverse effects on food intake and growth, (2) a decreased hepatic TAG and total cholesterol, irrespective of the difference in dietary fat level or feeding period, and (3) a decreased incorporation of [1(2)-(14)C] acetate and [1-(14)C] oleic acid into TAG of liver slices and hepatocytes.
Formal Description
Interaction-ID: 30416

environment

Momordica charantia methanol fraction supplementation

decreases_quantity of

drug/chemical compound

Cholesterol

in liver
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