General Information:

Id: 3,200 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Reference: Peters A et al.(2011) The selfish brain: stress and eating behavior Front Neurosci 5: 74 [PMID: 21660101]

Interaction Information:

Comment Because insulin is required for glucose uptake in the peripheral fat and muscle tissue via glucose transporter 4 (GLUT4), these postsynaptic VMH-neurons are able to limit glucose outflow the blood into the peripheral energy buffers. In this way, these allocative mechanisms are able to preserve blood glucose as a source for the insulin-independent glucose uptake via GLUT1 into the brain.
Formal Description
Interaction-ID: 29432

affects_activity of


glucose import

into the brain; via GLUT1 (SLC2A1)