General Information:

Id: 3,196 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Mammalia
rat;Tg2576 mouse
article
Reference: Kotilinek LA et al.(2008) Cyclooxygenase-2 inhibition improves amyloid-beta-mediated suppression of memory and synaptic plasticity Brain 131: 651-664 [PMID: 18292081]

Interaction Information:

Comment The non-selective NSAIDs (Non-steroid antiinflammatory drugs), ibuprofen and naproxen, are COX-2 inhibitors.
Formal Description
Interaction-ID: 29373

drug/chemical compound

Ibuprofen

decreases_activity of

gene/protein

PTGS2

Drugbank entries Show/Hide entries for Ibuprofen or PTGS2