General Information:

Id: 3,181 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Homo sapiens
M17 cell line; brain from AD patients
article
Reference: Sheng B et al.(2012) Impaired mitochondrial biogenesis contributes to mitochondrial dysfunction in Alzheimers disease J. Neurochem. 120: 419-429 [PMID: 22077634]

Interaction Information:

Comment The PKA/CREB pathway plays an important role in reduced expression of PGC-1a in APPswe M17 cells.
Formal Description
Interaction-ID: 29239

process

PKA/CREB pathway

affects_expression of

gene/protein

PPARGC1A

in APPswe M17 cells