CIDeRGeneral Information:
| Id: | 3,141 (click here to show other Interactions for entry) |
| Diseases: |
Diabetes mellitus, type II
- [OMIM]
Insulin resistance |
| Rattus norvegicus | |
| male | |
| Zucker rat, obese (OZR) or lean (LZR) | |
| article | |
| Reference: | Muller H et al.(2007) Angiotensin II stimulates the reactivity of the pituitary-adrenal axis in leptin-resistant Zucker rats, thereby influencing the glucose utilization. Am. J. Physiol. Endocrinol. Metab. 293: E802-E810 [PMID: 17595220] |
Interaction Information:
| Comment | The pituitary-adrenal axis (PA axis) is synergistically activated by angiotensin II (ANG II) and leptin resistance and that hyperreactivity is as a result paralleled by an impaired glucose utilization. |
|
Formal Description Interaction-ID: 28916 |
|
| Comment | The pituitary-adrenal axis (PA axis) is synergistically activated by angiotensin II (ANG II) and leptin resistance and that hyperreactivity is as a result paralleled by an impaired glucose utilization. |
|
Formal Description Interaction-ID: 28936 |
gene/protein decreases_activity of process glucose utilization |