General Information:

Id: 310 (click here to show other Interactions for entry)
Diseases: Amyotrophic lateral sclerosis
Mus musculus
SOD1 wt or SOD1G93A or SOD1G85R transgenic mouse, transfected with human wt SOD1 or human SOD1G93A or human SOD1G85R
BTO:0000312 motoneuron
Reference: Raoul C et al.(2006) Chronic activation in presymptomatic amyotrophic lateral sclerosis (ALS) mice of a feedback loop involving Fas, Daxx, and FasL Proc. Natl. Acad. Sci. U.S.A. 103: 6007-6012 [PMID: 16581901]

Interaction Information:

Comment Levels of Fas were similar between C57BL/6 and mutant SOD1 motoneurons and unchanged by the presence of NO donors such as Detanonoate.
Formal Description
Interaction-ID: 1228

drug/chemical compound


NOT affects_quantity of



in wt and mutant mice
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