General Information:

Id: 3,019 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Major depressive disorder - [OMIM]
Reference: Gragnoli C(2012) Depression and type 2 diabetes: Cortisol pathway implication and investigational needs J. Cell. Physiol. 227: 2318-2322 [PMID: 21898408]

Interaction Information:

Comment CRHR1 is expressed on pancreatic beta cells and potentiates glucose stimulated insulin secretion; activation of CRHR1 leads to proliferation of beta cells in neonatal rats.
Formal Description
Interaction-ID: 27773



increases_activity of

in pancreas, in pancreatic beta cells