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Field	Query

Alzheimer disease
Amyotrophic lateral sclerosis
Autism
Bipolar disorder
COXPD
Cancer
Cardiovascular diseases
Diabetes mellitus, type II
Epilepsy
Farber lipogranulomatosis
Inflammatory bowel disease
Lung disease
Major depressive disorder
Multiple sclerosis
Muscular atrophy
Neutropenia, severe congenital
Other
Parkinson disease
Post-traumatic stress disorder
Postpartum depression
Rare disease
Schizophrenia

	Field	Term

General Information:

Id:	3,019 (click here to show other Interactions for entry)
Diseases:	Diabetes mellitus, type II - [OMIM] Insulin resistance Major depressive disorder - [OMIM]
Organism:	Mammalia
Publication type:	review
Reference:	Gragnoli C(2012) Depression and type 2 diabetes: Cortisol pathway implication and investigational needs J. Cell. Physiol. 227: 2318-2322 [PMID: 21898408]

Interaction Information:

Comment	CRHR1 is expressed on pancreatic beta cells and potentiates glucose stimulated insulin secretion; activation of CRHR1 leads to proliferation of beta cells in neonatal rats.
Formal Description Interaction-ID: 27773	gene/protein CRHR1 increases_activity of process insulin secretion involved in cellular response to glucose stimulus in pancreas, in pancreatic beta cells

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