General Information:

Id: 3,012 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Homo sapiens
T4 cell; T4C3 cell
article
Reference: Quintanilla RA et al.(2009) Caspase-cleaved tau expression induces mitochondrial dysfunction in immortalized cortical neurons: implications for the pathogenesis of Alzheimer disease J. Biol. Chem. 284 [PMID: 19389700]

Interaction Information:

Comment T4C3 probably induces mitochondrial fragmentation through activation of calcium-dependent phosphatase calcineurin.
Formal Description
Interaction-ID: 27550

drug/chemical compound

Ca2+

affects_activity of

complex/PPI

Calcineurin