General Information:

Id: 297
Diseases: Amyotrophic lateral sclerosis
Homo sapiens
BTO:0001009 PC-12 cell
article
Reference: Sebastia J et al.(2009) Angiogenin protects motoneurons against hypoxic injury Cell Death Differ. 16: 1238-1247 [PMID: 19444281]

Interaction Information:

Comment Wild-type ANG showed significantly reduced levels of hypoxia-induced apoptosis, whereas the K40I or R31K mutant forms did not reduce the levels of apoptosis in response to hypoxia.
Formal Description
Interaction-ID: 1190

gene/protein

ANG

decreases_activity of

hypoxia induced
Drugbank entries Show/Hide entries for ANG
Comment Wild-type ANG showed significantly reduced levels of hypoxia-induced apoptosis, whereas the K40I or R31K mutant forms did not reduce the levels of apoptosis in response to hypoxia.
Formal Description
Interaction-ID: 1194

gene/protein mutant

ANG-p.K40I

NOT decreases_activity of

hypoxia induced
Comment Wild-type ANG showed significantly reduced levels of hypoxia-induced apoptosis, whereas the K40I or R31K mutant forms did not reduce the levels of apoptosis in response to hypoxia.
Formal Description
Interaction-ID: 1195

gene/protein mutant

ANG-p.R31K

NOT decreases_activity of

hypoxia induced