General Information:

Id: 2,977 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
MODY, type VI - [OMIM]
Mus musculus
neuroD beta-CKO mouse: mouse in which neuroD is deleted in insulin-expressing cells
article
Reference: Gu C et al.(2010) Pancreatic beta cells require NeuroD to achieve and maintain functional maturity Cell Metab 11: 298-310 [PMID: 20374962]

Interaction Information:

Comment Mice in which neuroD is deleted in insulin-expressing cells are severely deficient in glucosestimulated insulin secretion (GSIS), resulting in glucose intolerance.
Formal Description
Interaction-ID: 27108