General Information:

Id: 2,959 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
MODY, type I - [OMIM]
Reference: Stoffel M and Duncan SA(1997) The maturity-onset diabetes of the young (MODY1) transcription factor HNF4alpha regulates expression of genes required for glucose transport and metabolism Proc. Natl. Acad. Sci. U.S.A. 94 [PMID: 9371825]

Interaction Information:

Comment The study identified several genes encoding components of the glucose-dependent insulin secretion pathway whose expression is dependent upon HNF4alpha. These include glucose transporter 2, and the glycolytic enzymes aldolase B and glyceraldehyde-3-phosphate dehydrogenase, and liver pyruvate kinase.
Formal Description
Interaction-ID: 26992
Drugbank entries Show/Hide entries for HNF4A