General Information:

Id: 2,876 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Obesity - [OMIM]
Mus musculus
article
Reference: Steppan CM et al.(2001) The hormone resistin links obesity to diabetes. Nature 409: 307-312 [PMID: 11201732]

Interaction Information:

Comment Treatment of normal mice with recombinant resistin impairs glucose tolerance and insulin action. Insulin-stimulated glucose uptake by adipocytes is enhanced by neutralization of resistin and is reduced by resistin treatment.
Formal Description
Interaction-ID: 26496

gene/protein

RETN

decreases_activity of

process

glucose import

into adipocytes in adipose tissue