General Information:

Id: 2,848 (click here to show other Interactions for entry)
Diseases: Cancer
Diabetes mellitus, type II - [OMIM]
Insulin resistance
Homo sapiens
endometrial cancer cell lines, ECC-1 and BTO:0003041 Ishikawa
article
Reference: Cantrell LA et al.(2010) Metformin is a potent inhibitor of endometrial cancer cell proliferation--implications for a novel treatment strategy. Gynecol. Oncol. 116: 92-98 [PMID: 19822355]

Interaction Information:

Comment The endometrial cancer cell lines, ECC-1 and Ishikawa, were used. Metformin potently inhibited growth in a dose-dependent manner. Treatment with metformin resulted in G1 arrest, induction of apoptosis and decreased hTERT expression.
Formal Description
Interaction-ID: 26245

drug/chemical compound

Metformin

decreases_activity of

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