General Information:

Id: 2,831 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Homo sapiens
article
Reference: Hundal RS et al.(2000) Mechanism by which metformin reduces glucose production in type 2 diabetes. Diabetes 49: 2063-2069 [PMID: 11118008]

Interaction Information:

Comment The rate of gluconeogenesis was three times higher in the diabetic subjects than in the control subjects and metformin reduced that rate by 36%.
Formal Description
Interaction-ID: 26131

drug/chemical compound

Metformin

decreases_activity of

process

gluconeogenesis

in liver
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