General Information:

Id: 2,710 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Fatty liver disease, nonalcoholic
Insulin resistance
Obesity - [OMIM]
Reference: Ohtsubo K et al.(2011) Pathway to diabetes through attenuation of pancreatic beta cell glycosylation and glucose transport Nat Med 17: 1067-1075 [PMID: 21841783]

Interaction Information:

Comment Human type 2 diabetes islet cells had very low glucose transport activity and lacked the GSIS response.
Formal Description
Interaction-ID: 25309

decreases_activity of


glucose import

in pancreas, in pancreatic islets