CIDeRGeneral Information:
| Id: | 2,689 |
| Diseases: |
Endocrine
Postpartum depression |
| Mus musculus | |
| BTO:0000007 HEK-293 cell | |
| article | |
| Reference: | Schreiber SN et al.(2003) The transcriptional coactivator PGC-1 regulates the expression and activity of the orphan nuclear receptor estrogen-related receptor alpha (ERRalpha). J. Biol. Chem. 278: 9013-9018 [PMID: 12522104] |
Interaction Information:
| Comment | PGC-1 interacts physically with ERRalpha and enables it to activate transcription (potentially associated with postpartum depression). |
|
Formal Description Interaction-ID: 25170 |
|
| Drugbank entries | Show/Hide entries for ESRRA |
| Comment | PGC-1 interacts physically with ERRalpha and enables it to activate transcription. PGC-1 converts ERRalpha from a factor with little or no transcriptional activity to a potent regulator of gene expression (potentially associated with postpartum depression). |
|
Formal Description Interaction-ID: 25171 |
|
| Drugbank entries | Show/Hide entries for ESRRA |