General Information:

Id: 2,651 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Mus musculus
G6pc2 (-/-) mouse
Reference: Wang Y et al.(2007) Deletion of the gene encoding the islet-specific glucose-6-phosphatase catalytic subunit-related protein autoantigen results in a mild metabolic phenotype Diabetologia 50: 774-778 [PMID: 17265032]

Interaction Information:

Comment There were no statistically significant differences in plasma cholesterol, glycerol, insulin and glucagon concentrations between G6pc2-/- and wild-type mice. G6pc2-/- mice showed sex-related variation in the majority of these metabolic parameters that were in the same direction and of similar magnitude to the sex-related differences in wild-type mice.
Formal Description
Interaction-ID: 25030



NOT affects_quantity of

drug/chemical compound


in blood plasma
Drugbank entries Show/Hide entries for