General Information:

Id: 259
Diseases: Epilepsy, temporal lobe
Homo sapiens
BTO:0000007 HEK-293 cell
article
Reference: Lammich S et al.(2002) Presenilin-dependent intramembrane proteolysis of CD44 leads to the liberation of its intracellular domain and the secretion of an Abeta-like peptide. J. Biol. Chem. 277 [PMID: 12223485]

Interaction Information:

Comment The cleavage of CD44 requires a PS(presenilin 1)-dependent gamma-secretase activity.
Formal Description
Interaction-ID: 1060

gene/protein

PSEN1

affects_processing of

gene/protein

CD44