General Information:

Id: 2,578 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Mammalia
review
Reference: Lang V et al.(2011) The molecular genetics of sulfonylurea receptors in the pathogenesis and treatment of insulin secretory disorders and type 2 diabetes Curr. Diab. Rep. 11: 543-551 [PMID: 21968738]

Interaction Information:

Comment In pancreatic beta cells, K(ATP) channels play a vital role by acting as intracellular sensors of glucose metabolism, thus controlling insulin secretion.
Formal Description
Interaction-ID: 24270

complex/PPI

ATP-sensitive potassium channel complex

affects_activity of

in pancreas, in pancreatic beta cells