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Field	Query

Alzheimer disease
Amyotrophic lateral sclerosis
Autism
Bipolar disorder
COXPD
Cancer
Cardiovascular diseases
Diabetes mellitus, type II
Epilepsy
Farber lipogranulomatosis
Inflammatory bowel disease
Lung disease
Major depressive disorder
Multiple sclerosis
Muscular atrophy
Neutropenia, severe congenital
Other
Parkinson disease
Post-traumatic stress disorder
Postpartum depression
Rare disease
Schizophrenia

	Field	Term

General Information:

Id:	2,539 (click here to show other Interactions for entry)
Diseases:	Diabetes mellitus, type II - [OMIM] Insulin resistance
Organism:	Homo sapiens
Publication type:	article
Reference:	Ling C et al.(2008) Epigenetic regulation of PPARGC1A in human type 2 diabetic islets and effect on insulin secretion Diabetologia 51: 615-622 [PMID: 18270681]

Interaction Information:

Comment	PPARGC1A mRNA expression was reduced by 90% and correlated with the reduction in insulin secretion in islets from patients with type 2 diabetes.
Formal Description Interaction-ID: 23641	gene/protein PPARGC1A affects_activity of process insulin secretion

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