General Information:

Id: 2,533 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Mammalia
review
Reference: Di Paolo G and Kim TW(2011) Linking lipids to Alzheimers disease: cholesterol and beyond. Nat. Rev. Neurosci. 12: 284-296 [PMID: 21448224]

Interaction Information:

Comment The seeding property of GM1 increases with the ageing process and is facilitated by cholesterol-rich environments, indicating that the process might occur in membrane rafts.
Formal Description
Interaction-ID: 80188

drug/chemical compound

Cholesterol

increases_activity of

drug/chemical compound

Ganglioside GM1

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