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Diseases	Field	Query

Alzheimer disease
Amyotrophic lateral sclerosis
Autism
Bipolar disorder
COXPD
Cancer
Cardiovascular diseases
Diabetes mellitus, type II
Epilepsy
Farber lipogranulomatosis
Inflammatory bowel disease
Lung disease
Major depressive disorder
Multiple sclerosis
Muscular atrophy
Neutropenia, severe congenital
Other
Parkinson disease
Post-traumatic stress disorder
Postpartum depression
Rare disease
Schizophrenia

	Field	Term

General Information:

Id:	248
Diseases:	Epilepsy, temporal lobe Metabolic
Organism:	Homo sapiens
Tissue/Cell line:	BTO:0002126 U-373MG cel
Publication type:	article
Reference:	Deloulme JC et al.(2000) S100A6 and S100A11 are specific targets of the calcium- and zinc-binding S100B protein in vivo J. Biol. Chem. 275 [PMID: 10913138]

Interaction Information:

Comment	Ca(2+)/Zn(2+) stabilizes S100B-S100A6 heterocomplex.
Formal Description Interaction-ID: 1021	gene/protein S100B interacts (colocalizes) with gene/protein S100A6
Drugbank entries	Show/Hide entries for S100B
Drugbank DB00768	Olopatadine other/unknown S100B
Drugbank DB01373	Calcium not specified S100B
Drugbank DB04464	N-Formylmethionine not specified S100B
Drugbank DB06941	(Z)-2-[2-(4-methylpiperazin-1-yl)benzyl] ... not specified S100B
Drugbank DB07004	2-[(5-hex-1-yn-1-ylfuran-2-yl)carbonyl]- ... not specified S100B

Comment	Ca(2+)/Zn(2+) stabilizes S100B-S100A6 heterocomplex.
Formal Description Interaction-ID: 1022	drug/chemical compound Ca2+ affects_activity of complex/PPI S100A6-S100B complex

Comment	Ca(2+)/Zn(2+) stabilizes S100B-S100A6 heterocomplex.
Formal Description Interaction-ID: 1023	drug/chemical compound Zn2+ affects_activity of complex/PPI S100A6-S100B complex

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