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Field	Query

Alzheimer disease
Amyotrophic lateral sclerosis
Autism
Bipolar disorder
COXPD
Cancer
Cardiovascular diseases
Diabetes mellitus, type II
Epilepsy
Farber lipogranulomatosis
Inflammatory bowel disease
Lung disease
Major depressive disorder
Multiple sclerosis
Muscular atrophy
Neutropenia, severe congenital
Other
Parkinson disease
Post-traumatic stress disorder
Postpartum depression
Rare disease
Schizophrenia

	Field	Term

General Information:

Id:	2,417 (click here to show other Interactions for entry)
Diseases:	Diabetes mellitus, type II - [OMIM] Insulin resistance
Organism:	Homo sapiens
Organism Model:	Han Chinese
Publication type:	article
Reference:	Liu C et al.(2011) Variants in GLIS3 and CRY2 are associated with type 2 diabetes and impaired fasting glucose in Chinese Hans PLoS ONE 6 [PMID: 21747906]

Interaction Information:

Comment	GLIS3-rs7034200 showed significant associations with fasting glucose and HOMA-B, but not with BMI, HbA1c or HOMA-IR. None of the remaining eight loci (MADD-rs7944584, ADRA2A-rs10885122, CRY2-rs11605924, PROX1-rs340874, C2CD4B-rs11071657, IGF1-rs35767, IRS1- rs2943641 and FADS1-rs174550) were associated with any of glycemic traits, while a nominal association was observed between PROX1-rs340874 and BMI.
Formal Description Interaction-ID: 21752	SNP MADD rs7944584 NOT affects_activity of process insulin secretion in Han Chinese

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