General Information:

Id: 2,417 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Homo sapiens
Han Chinese
Reference: Liu C et al.(2011) Variants in GLIS3 and CRY2 are associated with type 2 diabetes and impaired fasting glucose in Chinese Hans PLoS ONE 6 [PMID: 21747906]

Interaction Information:

Comment GLIS3-rs7034200 showed significant associations with fasting glucose and HOMA-B, but not with BMI, HbA1c or HOMA-IR. None of the remaining eight loci (MADD-rs7944584, ADRA2A-rs10885122, CRY2-rs11605924, PROX1-rs340874, C2CD4B-rs11071657, IGF1-rs35767, IRS1- rs2943641 and FADS1-rs174550) were associated with any of glycemic traits, while a nominal association was observed between PROX1-rs340874 and BMI.
Formal Description
Interaction-ID: 21747

decreases_activity of

in Han Chinese