General Information:

Id: 240
Diseases: Alzheimer disease - [OMIM]
Rattus norvegicus
BTO:0000601 hippocampus
article
Reference: Mendes CT et al.(2009) Lithium reduces Gsk3b mRNA levels: implications for Alzheimer Disease Eur Arch Psychiatry Clin Neurosci 259: 16-22 [PMID: 18932008]

Interaction Information:

Comment Significant and dose-dependent inhibitory effects of lithium over the expression of Gsk3b were found, which was specific to hippocampal cells.
Formal Description
Interaction-ID: 998

drug/chemical compound

Lithium

decreases_expression of

gene/protein

GSK3B

in embryonic (E18) and adult rat brain
Drugbank entries Show/Hide entries for Lithium or GSK3B