General Information:

Id: 2,371 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Canis lupus familiaris
aged beagle
Reference: Barone E et al.(2011) Long-term high-dose atorvastatin decreases brain oxidative and nitrosative stress in a preclinical model of Alzheimer disease: a novel mechanism of action Pharmacol. Res. 63: 172-180 [PMID: 21193043]

Interaction Information:

Comment Atorvastatin significantly reduced lipoperoxidation, protein oxidation and nitration, and increased GSH levels in parietal cortex of aged beagles.
Formal Description
Interaction-ID: 20808

drug/chemical compound


decreases_activity of


lipid peroxidation

in parietal cortex of aged beagles
Drugbank entries Show/Hide entries for Atorvastatin