General Information:

Id: 2,269 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Canis lupus familiaris
article
Reference: Murphy MP et al.(2010) Changes in cognition and amyloid-beta processing with long term cholesterol reduction using atorvastatin in aged dogs. J. Alzheimers Dis. 22: 135-150 [PMID: 20847439]

Interaction Information:

Comment Secretase1 (BACE1) protein levels and activity decreased and correlated with reduced brain cholesterol in aged dogs.
Formal Description
Interaction-ID: 19404

drug/chemical compound

Cholesterol

affects_activity of

gene/protein

BACE1

Drugbank entries Show/Hide entries for Cholesterol or BACE1