General Information:

Id: 2,261 (click here to show other Interactions for entry)
Diseases: Neurological
Schizophrenia - [OMIM]
Mus musculus
article
Reference: Beaulieu JM et al.(2005) An Akt/beta-arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior. Cell 122: 261-273 [PMID: 16051150]

Interaction Information:

Comment The mice lacking both Arr2 and the DAT (dopamine transporter) do not display an inhibitory action of excessive DA (dopamine) on Akt phosphorylation. This demonstrates that D2R dopamine receptors regulate Akt through Arr2.
Formal Description
Interaction-ID: 19305

gene/protein

DRD2

affects_activity of

gene/protein

ARRB2

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