General Information:

Id: 2,249 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Dementia
Mammalia
review
Reference: Butterfield DA et al.(2011) Cholesterol-independent neuroprotective and neurotoxic activities of statins: perspectives for statin use in Alzheimer disease and other age-related neurodegenerative disorders Pharmacol. Res. 64: 180-186 [PMID: 21536132]

Interaction Information:

Comment The LEADe study did not support any significant positive effect of atorvastatin on cognitive or global functions in patients receiving the statin compared to those with placebo.
Formal Description
Interaction-ID: 19270

drug/chemical compound

Atorvastatin

NOT decreases_activity of

phenotype

cognitive impairment

(LEADe study)
Drugbank entries Show/Hide entries for Atorvastatin