General Information:

Id: 2,249 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Dementia
Mammalia
review
Reference: Butterfield DA et al.(2011) Cholesterol-independent neuroprotective and neurotoxic activities of statins: perspectives for statin use in Alzheimer disease and other age-related neurodegenerative disorders Pharmacol. Res. 64: 180-186 [PMID: 21536132]

Interaction Information:

Comment Atorvastatin treatment was neuroprotective against cell degeneration induced by Abeta (1-40), reducing inflammatory and oxidative responses and increasing the expression of glutamatergic transporters.
Formal Description
Interaction-ID: 19230

drug/chemical compound

Atorvastatin

increases_expression of

gene/protein

Glutamatergic transporter

Drugbank entries Show/Hide entries for Atorvastatin