General Information:

Id: 2,246
Diseases: Alzheimer disease - [OMIM]
Homo sapiens
cerebrospinal fluid (CSF)
article
Reference: Carlsson CM et al.(2008) Effects of simvastatin on cerebrospinal fluid biomarkers and cognition in middle-aged adults at risk for Alzheimers disease. J. Alzheimers Dis. 13: 187-197 [PMID: 18376061]

Interaction Information:

Comment Simvastatin use improved selected measures of cognitive function without significantly changing CSF Abeta42 or total tau levels.
Formal Description
Interaction-ID: 19172

drug/chemical compound

Simvastatin

decreases_activity of

phenotype

cognitive impairment

Drugbank entries Show/Hide entries for Simvastatin
Comment Simvastatin use improved selected measures of cognitive function without significantly changing CSF Abeta42 or total tau levels.
Formal Description
Interaction-ID: 19176

drug/chemical compound

Simvastatin

NOT affects_quantity of

in CSF
Drugbank entries Show/Hide entries for Simvastatin
Comment Simvastatin use improved selected measures of cognitive function without significantly changing CSF Abeta42 or total tau levels.
Formal Description
Interaction-ID: 19177

drug/chemical compound

Simvastatin

NOT affects_quantity of

gene/protein

MAPT

in CSF
Drugbank entries Show/Hide entries for Simvastatin