General Information:

Id: 218 (click here to show other Interactions for entry)
Diseases: Amyotrophic lateral sclerosis
Mus musculus
SOD1 wt or SOD1G93A transgenic mouse, transfected with human wt SOD1 or human SOD1G93A
BTO:0001279 spinal cord
article
Reference: Atkin JD et al.(2006) Induction of the unfolded protein response in familial amyotrophic lateral sclerosis and association of protein-disulfide isomerase with superoxide dismutase 1 J. Biol. Chem. 281 [PMID: 16847061]

Interaction Information:

Comment SOD1(G93A) mice induced the upregulation of the ER chaperones BiP, Erp57, and PDI at disease end stage p120.
Formal Description
Interaction-ID: 894

gene/protein mutant

SOD1-p.G93A

increases_quantity of

gene/protein

HSPA5

at disease end stage p120
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