General Information:

Id: 2,186 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Obesity - [OMIM]
Mus musculus
BTO:0000443 adipocyte
article
Reference: Talior I et al.(2003) Increased glucose uptake promotes oxidative stress and PKC-delta activation in adipocytes of obese, insulin-resistant mice. Am. J. Physiol. Endocrinol. Metab. 285: E295-E302 [PMID: 12857675]

Interaction Information:

Comment The activity of PKC-delta increased twofold in HF adipocytes compared with control adipocytes and was further activated by H2O2. Moreover, PKC-delta activity was inhibited in HF adipocytes either by glucose deprivation or by treatment with the antioxidant N-acetyl-l-cysteine.
Formal Description
Interaction-ID: 18316

drug/chemical compound

H2O2

increases_activity of

gene/protein

PRKCD

in adipose tissue
Drugbank entries Show/Hide entries for PRKCD