CIDeRGeneral Information:
| Id: | 2,186 (click here to show other Interactions for entry) |
| Diseases: |
Diabetes mellitus, type II
- [OMIM]
Insulin resistance Obesity - [OMIM] |
| Mus musculus | |
| BTO:0000443 adipocyte | |
| article | |
| Reference: | Talior I et al.(2003) Increased glucose uptake promotes oxidative stress and PKC-delta activation in adipocytes of obese, insulin-resistant mice. Am. J. Physiol. Endocrinol. Metab. 285: E295-E302 [PMID: 12857675] |
Interaction Information:
| Comment | The adipocytes used were isolated either from C57Bl/6J mice that were raised on a high-fat diet (HF) and developed obesity and insulin resistance or from control animals. Basal glucose uptake significantly increased (8-fold) in HF adipocytes, and this was accompanied with upregulation of GLUT1 expression levels. |
|
Formal Description Interaction-ID: 18308 |
environment high-fat diet increases_activity of process |