General Information:

Id: 2,172 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Obesity - [OMIM]
Rattus norvegicus
male
article
Reference: Boustany CM et al.(2004) Activation of the systemic and adipose renin-angiotensin system in rats with diet-induced obesity and hypertension. Am. J. Physiol. Regul. Integr. Comp. Physiol. 287: R943-R949 [PMID: 15191907]

Interaction Information:

Comment A marked increase in the plasma concentrations of ANG II was determined in obesity-prone (OP) rats compared with obesity-resistant and low-fat fed rats. Moreover, elevations in plasma concentrations of ANG III and ANG 5-8 were detected in OP rats, giving rise to a threefold increase in the sum of circulating ANG peptides in OP rats.
Formal Description
Interaction-ID: 18188

disease

Obesity

increases_quantity of

gene/protein

Angiotensin II

in blood
Comment Plasma ANG II concentrations correlated positively to MAP in all rats from this study.
Formal Description
Interaction-ID: 18191

gene/protein

Angiotensin II

increases_activity of