General Information:

Id: 2,122 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Rattus norvegicus
male
streptozotocin-induced diabetes
article
Reference: Van Linthout S et al.(2009) Vascular-protective effects of high-density lipoprotein include the downregulation of the angiotensin II type 1 receptor. Hypertension 53: 682-687 [PMID: 19273745]

Interaction Information:

Comment HDL reduced the responsiveness to Ang II, as indicated by decreased oxidative stress in the hyperglycemia+HDL+Ang II group compared with the hyperglycemia+Ang II group, vascular-protective effects of HDL include the downregulation of the AT1R.
Formal Description
Interaction-ID: 17403

complex/PPI

HDL

decreases_activity of

gene/protein

Angiotensin II