General Information:

Id: 2,119 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Rattus norvegicus
male
article
Reference: Oelze M et al.(2006) Nebivolol inhibits superoxide formation by NADPH oxidase and endothelial dysfunction in angiotensin II-treated rats. Hypertension 48: 677-684 [PMID: 16940222]

Interaction Information:

Comment The novel beta1-receptor blocker nebivolol but not metoprolol prevents Ang II induced NOS III uncoupling.
Formal Description
Interaction-ID: 17386

gene/protein

Angiotensin II

decreases_activity of

gene/protein

NOS3

via uncoupling of the active homodimer
Drugbank entries Show/Hide entries for NOS3