General Information:

Id: 2,040
Diseases: Alzheimer disease - [OMIM]
Homo sapiens
article
Reference: Zhou R et al.(2011) Association between Bone Mineral Density and the Risk of Alzheimers Disease. J. Alzheimers Dis. 24: 101-108 [PMID: 21187587]

Interaction Information:

Comment Alzheimer's disease (AD) and osteoporosis are common chronic degenerative disorders which are strongly associated with advanced age.
Formal Description
Interaction-ID: 16313

process

aging

increases_activity of

phenotype

osteoporosis

Comment Alzheimer's disease (AD) and osteoporosis are common chronic degenerative disorders which are strongly associated with advanced age.
Formal Description
Interaction-ID: 16314

process

aging

increases_activity of

Comment Low BMD and increased loss rate of BMD were associated with higher risk of AD in both women and men.
Formal Description
Interaction-ID: 16315

increases_activity of

Comment A higher leptin level is associated with decreased risk of AD.
Formal Description
Interaction-ID: 16316

decreases_activity of

Comment A link between osteoporosis and AD is that they share some common risk factors, such as current smoking, daily drinking, and low leptin levels.
Formal Description
Interaction-ID: 16317

increases_activity of

phenotype

osteoporosis

Comment A link between osteoporosis and AD is that they share some common risk factors, such as current smoking, daily drinking, and low leptin levels.
Formal Description
Interaction-ID: 16318

environment

cigarette smoking

increases_activity of

phenotype

osteoporosis

Comment A link between osteoporosis and AD is that they share some common risk factors, such as current smoking, daily drinking, and low leptin levels.
Formal Description
Interaction-ID: 16319

environment

cigarette smoking

increases_activity of

Comment Smoking is also a risk factor of osteoporosis. It has been found that current smokers have decreased BMD than non-smokers. The impact of smoking on bone status is associated with the smoking year and amount.
Formal Description
Interaction-ID: 16320

increases_activity of

phenotype

osteoporosis