General Information:

Id: 2,039 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Mus musculus
article
Reference: Mitsuishi M et al.(2009) Angiotensin II reduces mitochondrial content in skeletal muscle and affects glycemic control. Diabetes 58: 710-717 [PMID: 19074984]

Interaction Information:

Comment The AngII-induced reduction in mitochondrial proteins involved in electron transport or fatty acid oxidation (ATP synthase, COX, and medium-chain fatty acyl-CoA dehydrogenase) were all suppressed by blockade of either AT1R or AT2R.
Formal Description
Interaction-ID: 16293

gene/protein

Angiotensin II

decreases_quantity of

complex/PPI

Mitochondrial respiratory chain complex V

in mitochondria; via AGTR1 or AGTR2