General Information:

Id: 2,035 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Homo sapiens
brain tissue from AD patients with severe CAA
Reference: Schrag M et al.(2011) Effect of cerebral amyloid angiopathy on brain iron, copper, and zinc in Alzheimers disease. J. Alzheimers Dis. 24: 137-149 [PMID: 21187585]

Interaction Information:

Comment Patients with severe CAA had significantly higher non-heme iron levels compared to AD patients without evidence of vascular amyloid-beta. Histologically, iron was deposited in the walls of large CAA-affected vessels.
Formal Description
Interaction-ID: 16168

drug/chemical compound

Iron, non-heme

is localized in

tissue/cell line

blood vessel wall

of large CAA-affected vessels