General Information:

Id: 2,020 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Obesity - [OMIM]
Homo sapiens
female
article
Reference: Gorzelniak K et al.(2002) Hormonal regulation of the human adipose-tissue renin-angiotensin system: relationship to obesity and hypertension J. Hypertens. 20: 965-973 [PMID: 12011658]

Interaction Information:

Comment Hydrocortisone increased angiotensin II type 1 receptor gene and protein expression in a time- and dose-dependent manner in human adipocytes, but had no significant influence on other renin-angiotensin system genes,i.e. AGT, REN, ACE, and AT2. Gene expression of these five RAS genes were also not significantly affected by stimulation with insulin, 17-beta-estradiol, 3,3',5-triiodo-L-thyronine, or angiotensin II.
Formal Description
Interaction-ID: 16027

gene/protein

Angiotensin II

NOT affects_expression of

gene/protein

ACE

in adipose tissue
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