General Information:
Id: | 2,019 (click here to show other Interactions for entry) |
Diseases: |
Diabetes mellitus, type II
- [OMIM]
Insulin resistance |
Mus musculus | |
male | |
BTO:0001456 white adipose tissue | |
article | |
Reference: | Saint-Marc P et al.(2001) Angiotensin II as a trophic factor of white adipose tissue: stimulation of adipose cell formation. Endocrinology 142: 487-492 [PMID: 11145613] |
Interaction Information:
Comment | Based upon in vivo and ex vivo experiments combined to immunocytochemical staining of glycerol-3-phosphate dehydrogenase (GPDH), an indicator of adipocyte formation, it is reported herein that AngII favors the appearance of GPDH-positive cells. In the presence of a cyclooxygenase inhibitor, this adipogenic effect is abolished, whereas that of (carba)prostacyclin, a stable analog of prostacyclin that bypasses this inhibition, appears unaltered. |
Formal Description Interaction-ID: 15999 |
gene/protein increases_activity of process |