General Information:
Id: | 2,009 (click here to show other Interactions for entry) |
Diseases: |
Diabetes mellitus, type II
- [OMIM]
Insulin resistance |
Rattus norvegicus | |
male | |
Ren-2 rat: transgenic hypertensive TG(mREN-2)27 rat | |
article | |
Reference: | Blendea MC et al.(2005) Abrogation of oxidative stress improves insulin sensitivity in the Ren-2 rat model of tissue angiotensin II overexpression Am. J. Physiol. Endocrinol. Metab. 288: E353-E359 [PMID: 15494608] |
Interaction Information:
Comment | Improvements in skeletal muscle insulin-dependent glucose uptake and whole body IR in rats overexpressing ANG II by ARB or SOD mimetic indicate that oxidative stress plays an important role in ANG II-mediated insulin resistance. |
Formal Description Interaction-ID: 15958 |
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