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Field	Query

Alzheimer disease
Amyotrophic lateral sclerosis
Autism
Bipolar disorder
COXPD
Cancer
Cardiovascular diseases
Diabetes mellitus, type II
Epilepsy
Farber lipogranulomatosis
Inflammatory bowel disease
Lung disease
Major depressive disorder
Multiple sclerosis
Muscular atrophy
Neutropenia, severe congenital
Other
Parkinson disease
Post-traumatic stress disorder
Postpartum depression
Rare disease
Schizophrenia

	Field	Term

General Information:

Id:	2,009 (click here to show other Interactions for entry)
Diseases:	Diabetes mellitus, type II - [OMIM] Insulin resistance
Organism:	Rattus norvegicus
Gender:	male
Organism Model:	Ren-2 rat: transgenic hypertensive TG(mREN-2)27 rat
Publication type:	article
Reference:	Blendea MC et al.(2005) Abrogation of oxidative stress improves insulin sensitivity in the Ren-2 rat model of tissue angiotensin II overexpression Am. J. Physiol. Endocrinol. Metab. 288: E353-E359 [PMID: 15494608]

Interaction Information:

Comment	Insulin-mediated 2-deoxyglucose (2-DG) uptake was substantially lower in Ren-2 rat soleus muscle compared with controls. However, Ren-2 rats treated with valsartan or tempol exhibited a significant increase in insulin-mediated 2-DG uptake compared with untreated transgenic animals.
Formal Description Interaction-ID: 15957	drug/chemical compound Tempol increases_activity of process glucose import in soleus muscle; in Ren-2 rats

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