General Information:
Id: | 2,002 (click here to show other Interactions for entry) |
Diseases: |
Diabetes mellitus, type II
- [OMIM]
Insulin resistance |
Mus musculus | |
BTO:0004578 vascular smooth muscle cell | |
article | |
Reference: | Zhang F et al.(2010) Different effects of angiotensin II and angiotensin-(1-7) on vascular smooth muscle cell proliferation and migration. PLoS ONE 5 [PMID: 20808802] |
Interaction Information:
Comment | The ERK1/2 signaling pathway plays a major role in Ang II-induced SMC proliferation and migration. Ang II treatment stimulated phosphorylation of ERK1/2 and that this effect was significantly inhibited in the presence of Ang-(1-7). |
Formal Description Interaction-ID: 15897 |
gene/protein increases_phosphorylation of gene/protein MAPK3/1 |