General Information:

Id: 2,002 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Mus musculus
BTO:0004578 vascular smooth muscle cell
article
Reference: Zhang F et al.(2010) Different effects of angiotensin II and angiotensin-(1-7) on vascular smooth muscle cell proliferation and migration. PLoS ONE 5 [PMID: 20808802]

Interaction Information:

Comment The ERK1/2 signaling pathway plays a major role in Ang II-induced SMC proliferation and migration. Ang II treatment stimulated phosphorylation of ERK1/2 and that this effect was significantly inhibited in the presence of Ang-(1-7).
Formal Description
Interaction-ID: 15897

gene/protein

Angiotensin II

increases_phosphorylation of

gene/protein

MAPK3/1

in vascular smooth muscle