General Information:

Id: 1,987 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Homo sapiens
female
primary cultured human preadipocytes
article
Reference: Janke J et al.(2002) Mature adipocytes inhibit in vitro differentiation of human preadipocytes via angiotensin type 1 receptors. Diabetes 51: 1699-1707 [PMID: 12031955]

Interaction Information:

Comment Inhibition of adipogenic differentiation by Ang II and stimulation by AT1 receptor blockade with irbesartan was also accompanied by a respective decrease or increase in expression of the adipogenic marker genes PPAR-gamma and FAS.
Formal Description
Interaction-ID: 15603

gene/protein

Angiotensin II

decreases_expression of

gene/protein

FASN

in adipose tissue
Drugbank entries Show/Hide entries for FASN