General Information:

Id: 1,987 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Homo sapiens
female
primary cultured human preadipocytes
article
Reference: Janke J et al.(2002) Mature adipocytes inhibit in vitro differentiation of human preadipocytes via angiotensin type 1 receptors. Diabetes 51: 1699-1707 [PMID: 12031955]

Interaction Information:

Comment In contrast to stimulation with Ang II, AT1 receptor blockade with irbesartan increased lipid accumulation. Increased lipid accumulation was attributable to both an increased number of differentiated cells and an increase in intracytoplasmic lipid accumulation.
Formal Description
Interaction-ID: 15599

gene/protein

Angiotensin II

decreases_quantity of

drug/chemical compound

Lipid

in adipose tissue