General Information:

Id: 1,987 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Homo sapiens
female
primary cultured human preadipocytes
article
Reference: Janke J et al.(2002) Mature adipocytes inhibit in vitro differentiation of human preadipocytes via angiotensin type 1 receptors. Diabetes 51: 1699-1707 [PMID: 12031955]

Interaction Information:

Comment Incubation with Ang II or AGT resulted in a dose-dependent inhibition of adipogenic differentiation, despite concomitant stimulation with the differentiation cocktail (insulin plus hydrocortisone plus T3).
Formal Description
Interaction-ID: 15597

gene/protein

Angiotensin II

decreases_activity of

process

fat cell differentiation

in adipose tissue