General Information:

Id: 1,978 (click here to show other Interactions for entry)
Diseases: Cardiovascular disease
Diabetes mellitus, type II - [OMIM]
Insulin resistance
Rattus norvegicus
male
article
Reference: Velloso LA et al.(1996) Cross-talk between the insulin and angiotensin signaling systems Proc. Natl. Acad. Sci. U.S.A. 93 [PMID: 8901609]

Interaction Information:

Comment The phosphorylation of IRS1 and IRS2 following the injection of angiotensin II appears to involve JAK2 tyrosine kinase, which associates with the AT1 receptor and IRS-1/IRS-2 after AII stimulation.
Formal Description
Interaction-ID: 15521

gene/protein

Angiotensin II

affects_activity of

gene/protein

JAK2

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