General Information:

Id: 196 (click here to show other Interactions for entry)
Diseases: Amyotrophic lateral sclerosis
Mus musculus
SOD1 wt or SOD1G93A transgenic mouse, transfected with human wt SOD1 or human SOD1G93A
BTO:0001279 spinal cord; BTO:0000312 motoneuron
article
Reference: Kieran D et al.(2007) Deletion of the BH3-only protein puma protects motoneurons from ER stress-induced apoptosis and delays motoneuron loss in ALS mice. Proc. Natl. Acad. Sci. U.S.A. 104 [PMID: 18077368]

Interaction Information:

Comment The expression of the ER-resident chaperones Grp78 and Grp94 in motoneurons of SOD1G93A mice increased as early as 50 days compared with WT littermates.
Formal Description
Interaction-ID: 786

gene/protein mutant

SOD1-p.G93A

increases_quantity of

gene/protein

HSPA5

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